I know, I know its been done to death but who here doesn't love when video games involve inflation.
Here is a list of some games I haven't seen listed here before:
Eternal Darkness (Gamecube). Personally haven't seen it myself, however through many sources I have been informed there is a breast expansion "Easter egg" involving the main female character. Props to someone who finds/knows of this
Haunting Grounds (PS2) A resident evil type game which features a female lead.